The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis

Dacryocystitis Clinical Trial

Official title:

The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03216642
• Other study ID #: 2017019
• Status: Recruiting
• Phase: N/A
• First received: July 7, 2017
• Last updated: July 26, 2017
• Start date: July 17, 2017
• Est. completion date: April 17, 2018

Study information

• Verified date: July 2017
• Source: Sun Yat-sen University
• Contact: Zhang Xiulan, M.D.
• Phone: 02087335367
• Email: zhangxl2[@]mail.sysu.edu.cn
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

An observational study was designed to research the bacteriology and pathogen drug sensitivity of chronic dacryocystitis in China and optimize antibiotic therapy.

Description:

For patients diagnosed with chronic dacryocystitis，we will collect the secretions after lacrimal passage irrigation, note the characters of the secretions and send the secretions for bacteria culture, analysis and pathogen drug sensitivity.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: April 17, 2018
• Est. primary completion date: April 17, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

1. Diagnosed with chronic dacryocystitis

2. No involvement in other drug experiment in the past 1 week

Exclusion Criteria:

1. Can not cooperate the specimen collection

2. With any other eye disease

Related Conditions & MeSH terms

• Bacteriology
• Dacryocystitis
• Hypersensitivity

Intervention

Diagnostic Test:
• bacterial culture and analysis
Specimens were collected with soft-tipped applicators of sterile cotton swabs after syphilis of lacrimal passages.

Locations

Country	Name	City	State
China	Clinical Research Center	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Sun Yat-sen University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Bacterial agents	Specimens will be collected after irrigation of the lacrimal passage and be sent for bacterial culture and bacterial analysis.	2 weeks
Secondary	Sensitivity test	The drugs tested include Penicilin, Amikacin, Azithromycin, Cefoxitin, Levofloxacin,Ofloxacin, Cefuroxime and Tobramycin.	2 weeks
Secondary	The colour of lacrimal sac secretion	The colour of lacrimal sac secretion will be identified by the doctor during the irrigation of the lacrimal passage.	2 weeks
Secondary	The character of lacrimal sac secretion	The lacrimal sac secretion will be classified as mucus or pus.	2 weeks