Effect of Cranberry Extract on the Urinary System

Cystitis Clinical Trial

Official title:

Effects of Use of Cranberry Extract Instead of Antibiotics During Uncomplicated Urinary Tract Infection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05260554
• Other study ID #: Kirklareli University
• Status: Completed
• Start date: January 26, 2022
• Est. completion date: February 18, 2022

Study information

• Verified date: February 2022
• Source: Kirklareli University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Description:

This study was Istanbul Kartal Dr. Lütfi Kırdar Training and Research Hospital Emergency Medicine Clinic and Kırklareli Training and Research Hospital Emergency Service and Internal Medicine Polyclinic. Our study; includes patients who applied to the Emergency Department and Internal Medicine outpatient clinic with the complaint of dysuria and had normal WBC, CRP, urea, and creatinine values in their analysis, and leukocyturia was found in the urine test. Two options were offered in the treatment to these patients. Vaccinium Macrocarpon Aiton preparation or fosfomycin was given for seven days. The patients were asked whether their complaints had decreased according to the Lykert-Type verbal scale at the time of admission and on the first, third, and seventh days. When the treatment was finished, leukocytes were checked in the urinalysis. This outcome was compared between the 2 treatment options. We also noted whether nausea.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2
• Est. completion date: February 18, 2022
• Est. primary completion date: February 18, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Older than 18
• who have urinary tract inflammation
• who haven't kidney dissease previous

Exclusion Criteria:

• Younger than 18
• Who have kidney inflammation
• Pregnant patients
• Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)

Related Conditions & MeSH terms

• Antibiotic Reaction
• Cystitis
• Urinary Tract Disease
• Urologic Diseases

Intervention

Drug:
• Fosfomycin
In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.

Dietary Supplement:
• Cranberry
In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.

Locations

Country	Name	City	State
Turkey	Oya Guven, MD	Kirklareli	Center

Sponsors (1)

Lead Sponsor	Collaborator
Kirklareli University

Country where clinical trial is conducted

Turkey, 

References & Publications (1)

Gray M. Are cranberry juice or cranberry products effective in the prevention or management of urinary tract infection? J Wound Ostomy Continence Nurs. 2002 May;29(3):122-6. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Treatment time	After 7 days of treatment, the 2 treatment options were compared with each other.	7 days