Two Cases of Pulmonary Cysticercosis Manifesting as Pleural Effusion: Case Report and Literature Review

Cysticercosis Clinical Trial

Official title:

Two Cases of Pulmonary Cysticercosis Manifesting as Pleural Effusion: Case Report and Literature Review

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05010811
• Other study ID #: 2016-122
• Status: Completed
• Start date: October 22, 2016
• Est. completion date: April 28, 2017

Study information

• Verified date: September 2016
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Isolation lung cysticercosis reports are rare in literature. Most lung lesions were characterized by nodules. The investigators access one case which was characterized with pulmonary cavity and pleural effusion by Gupta N, et al in 2015 from PUBMED and Medline. But pleural effusion and exudative lesions is reported for the first time.

Description:

Cysticercosis is an important public health problem in developing countries. The major involvement sites are the central nervous system and the eyes，although striated muscles and subcutaneous tissues are frequently involved in the disseminated form of disease. Pulmonary involvement in cysticercosis is very rare and ill-defined nodular shadows distributed throughout the lung is the usual radiological presentation. Only one case of cysticercosis presenting as lung cavity with pleural effusion has been reported so far in literature. The investigators describe two cases in which pleural effusion due to cysticercosis were detected on X and CT.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2
• Est. completion date: April 28, 2017
• Est. primary completion date: January 18, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 45 Years to 67 Years

Eligibility

Inclusion Criteria:

1. Clinical diagnosis of Pulmonary Cysticercosis?

2. With pleural effusion

Exclusion Criteria:

1.No cysticercosis was found by biopsy or antibody test

Related Conditions & MeSH terms

• Cysticercosis
• Neurocysticercosis
• Pleural Effusion

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Amount of pleural effusion	cm	9 months
Primary	Rate of Eosinophil ratio	Percentage(%)	9 months
Primary	Changes of lesions under chest radiography or CT	no change, change, complete absorption	9 months