Benign Solitary Solid Clinical Trial
Official title:
Ultrasound Guided Interstitial Laser Photocoagulation on Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who
undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion.
Nodules left untreated seem to have a slight growth potential in borderline iodine-deficient
areas. Interstitial laser photo-coagulation (ILP) is a procedure for local hyperthermia and
photocoagulation, allowing minimally invasive treatment of benign tumors, including thyroid
nodules. The aim of these studies are to evaluate if ILP will be useful in reducing the
volume of the benign thyroid nodule and thyroid function will be unaffected in euthyroid
patients, and normalized in pretoxic- and toxic thyroid nodules. The investigations are
listed below:
1. Randomized study of interstitial laser photocoagulation for benign solitary cold
thyroid nodules – one versus two or three treatments
2. Randomized study of interstitial laser photocoagulation for benign solitary autonomous
thyroid nodules – 131I versus laser ablation
3. Interstitial laser photocoagulation for benign thyroid cystadenomas. – a feasibility
study.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment