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Clinical Trial Summary

This study will evaluate the tolerability and effectiveness of three FDA-approved treatments in Neurofibromatosis Type 1 Cutaneous Neurofibromas. These treatments are: a 1064nm laser, a 755nm laser, and a Kybella injection. Each patient will have a treatment and a control site.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04730583
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Active, not recruiting
Phase Phase 1
Start date June 2, 2021
Completion date December 2024

See also
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Completed NCT05005845 - NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) Phase 2
Active, not recruiting NCT05438290 - DPCP to Treat Cutaneous Neurofibromas Associated With NF1 Phase 1
Not yet recruiting NCT03105258 - Selumetinib Pilot Study for Cutaneous Neurofibromas Phase 2
Recruiting NCT05581511 - Natural History Study of Cutaneous Neurofibromas in People With NF1
Completed NCT03090971 - Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1 Phase 2
Recruiting NCT06159166 - Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF). Phase 1/Phase 2
Completed NCT02839720 - Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma Phase 2
Completed NCT04435665 - NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) Phase 2
Active, not recruiting NCT05119582 - HIFU Treatment of Cutaneous Neurofibromas in Neurofibromatosis Type 1: Safety and Efficacy N/A