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Clinical Trial Summary

The aim of this study is to develop and assess the feasibility and effect of a web-based, personalized risk-estimation for Crohn's disease (PRE-CD) tool on behaviors and biomarkers associated with risk for Crohn's disease in unaffected first-degree relatives of patients with inflammatory bowel disease. We hypothesize that personalized risk disclosure via the PRE-CD educational tool is both feasible and successful in modifying behaviors associated with Crohn's disease risk and normalizing pre-clinical disease biomarkers when compared to standard Crohn's disease education. Broadly, completion of this project will also help elucidate the role of lifestyle and dietary factors in pre-clinical Crohn's disease development in high-risk individuals, and provide novel insight into potential strategies for disease prevention in this population.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05332639
Study type Interventional
Source Massachusetts General Hospital
Contact Emily Lopes, MD
Phone 617-726-5560
Email mghprecd@partners.org
Status Not yet recruiting
Phase N/A
Start date February 2025
Completion date August 2026

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