Crohn's Disease Clinical Trial
Official title:
Mediterranean Diet vs. Low Residue Diet as an add-on Therapy for Induction of Remission in Patients With Active Crohn's Disease
This clinical study is designed to evaluate the effect of Mediterranean diet as an add-on therapy for induction of remission in adult patients with active Crohn's disease and to evaluate its effects on clinical, inflammatory and microbial parameters.
The Mediterranean diet has been associated with anti-inflammatory properties and with
decreased risk for several chronic diseases. However, the effect of Mediterranean diet has
not been evaluated in patients with inflammatory bowel diseases.
The purpose of this study is to determine whether Mediterranean diet is superior to a low
residue diet as an add-on therapy for induction of remission in adult patients with active
Crohn's disease and to evaluate its effects on clinical, inflammatory and microbial
parameters.
Seventy eligible patients will be randomly assigned to one of two dietary interventions:
Mediterranean diet or low residue diet, as an add-on therapy for induction of remission of
active Crohn's disease. The effect of the dietary regimens on clinical, inflammatory and
microbial parameters will be assessed at 8 and 52 weeks.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment
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