Crohn's Disease Clinical Trial
Official title:
The Diagnostic Methods of Crohn's Disease Flare-up Within One Month After Resection
Crohn's disease is a chronic inflammatory transmural bowel disorder characterized by high
rate of postoperative anastomotic complications and recurrences. Surgery itself can
influence immunologic function and trigger inflammatory response, which may result in the
flare of Crohn's disease soon after surgery (within one month), especially near the
anastomosis. Early flare-up of Crohn's disease can negatively impact the outcomes of
operation. However, due to the the complexity of perioperative period and dangerous of
invasive examine, it is difficult to distinguish disease flare from postoperative
complications.
In this study, the investigators aim to development a diagnostic method of flare-up within
one month after surgery, which can help us to detect and then treat disease flare in time.
HBI score, serum CRP, ESR, WBC, Hb, PLT, IL-6，PCT and fecal Calprotectin will be monitored within one month after resection. ;
Observational Model: Case Control, Time Perspective: Prospective
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