Transplantation of Bone Marrow Mesenchymal Stem Cell in Crohn's Disease

Status Recruiting

Clinical Trial Summary

This study is a prospective, randomized, parallel, phase 1 trial to assess the safety and feasibility of the transplantation of bone marrow derived mesenchymal stem cells (MSCs) in fistulizing Crohn's disease.

Clinical Trial Description

In this study all eligible patients were randomly allocated into two study groups by a permuted block randomization method: group A receives only autologous MSCs suspended in fibrin glue, group B receives autologous MSCs+ Fibroblasts. Both groups receive 4 injections inside the wall and lumen of the fistula. Injections will be repeated every month. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01874015
Study type	Interventional
Source	Royan Institute
Contact	Nasser Aghdami, MD,PhD
Phone	+9823562000
Email	nasser.aghdami@royaninstitute.org
Status	Recruiting
Phase	Phase 1
Start date	February 2013
Completion date	February 2018

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