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Anastomotic Leakage and Value Of Indocyanine Green in Decreasing Leakage Rates — AVOID  

Crohn Disease Clinical Trial

Official title:
A PHASE III, RANDOMISED CONTROLLED TRIAL ASSESSING THE VALUE OF INDOCYANINE GREEN IN THE LEAKAGE RATE OF COLORECTAL ANASTOMOSES

Clinical Trial Summary

Anastomotic leakage (AL) is one of the major complications after gastrointestinal surgery. Compromised tissue perfusion at the anastomosis site increases the risk of AL. Indocyanine green (ICG) combined with fluorescent near infrared imaging has proven to be a feasible and reproducible application for real-time intraoperative quantification of the tissue perfusion and cohort studies showed reduced leakage rate. Unfortunately, these studies were not randomized. Therefore, we propose a nationwide randomized controlled trial to identify the value of ICG for AL in colorectal anastomosis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04712032
Study type Interventional
Source Leiden University Medical Center
Contact Alexander Vahrmeijer, MD, PhD
Phone 071 526 9111
Email a.l.vahrmeijer@lumc.nl
Status Recruiting
Phase Phase 3
Start date July 1, 2020
Completion date October 1, 2022
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