Contrast Enhanced Ultrasound in Human Crohn's Disease-Lumason

Status Active, not recruiting

Clinical Trial Summary

The investigators plan to compare contrast-enhanced ultrasound to CT and MRI for the detection and quantification of intestinal inflammation in the the setting of pediatric small bowel Crohns disease

Clinical Trial Description

The proposed study will investigate the use of an FDA-approved ultrasound microbubble contrast agent (Lumason; Bracco Diagnostics) in pediatric and adult Crohn's disease patients undergoing either MR enterography (MRE, or MRI of the bowel) or CT enterography (CTE, or CT of the bowel). In April 2016, Lumason was FDA approved for intravenous administration and imaging of the liver in children. Imaging of the bowel will employ an identical administration method to that described for liver imaging, but the ultrasound transducer will be placed over the affected intestines as opposed to liver. ;

Study Design

Related Conditions & MeSH terms

Crohn Disease

Clinical Trial Details

NCT number	NCT03492944
Study type	Observational
Source	Children's Hospital Medical Center, Cincinnati
Contact
Status	Active, not recruiting
Phase
Start date	March 6, 2020
Completion date	January 2025

View Details

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