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Stem Cells Treatment of Complex Crohn's Anal Fistula — fistula  

Crohn Disease Clinical Trial

Official title:
Stem Cells Treatment of Complex Crohns Perianal Fistula. A Pilot Clinical Study

Clinical Trial Summary

A pilot study to investigate the safety and feasibility of stem cells treatment of complex anal fistula in patients with Crohn's disease.

Clinical Trial Description

Stem cells therapy in the management of soft tissue healing has been shown to be safe and feasible with encouraging short-term results both for crypto glandular and Crohns anal fistula. The long-term results are still insufficient but based on only a few studies conducted with small patient series and various techniques and type of stem cells. In the present study the patient's own adipose tissue derived regenerative cells (ADRCs) will be used. Traditionally the stem cells are injected into the fistula tract; however survival and retaining the stem cells in the fistula tract is problematic. Alternatively, one may apply stem cells enriched fatty tissue around and into the fistula tract. The aim of this project is to develop a method for treatment of patients with Crohns fistula. The results of conventional surgery are disappointing and followed by a high degree of recurrence and complications. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03466515
Study type Interventional
Source University of Southern Denmark
Contact
Status Completed
Phase N/A
Start date June 1, 2018
Completion date December 31, 2020
View Details
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