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Efficacy of PRUcalopride in Critically Ill Patients With Paralytic ILeus — EPRUCIL  

Critically Ill Clinical Trial

Official title:
Efficacy of Prucalopride in Critically Ill Patients With Paralytic Ileus; a Pilot Randomized Double-blind Controlled Trial

Clinical Trial Summary

Paralytic ileus is a common intestinal dysfunction in critically ill patients. There are still no established the effective medications except correcting the primary causes and prokinetics trial which limited in efficacy and potential adverse events.

Clinical Trial Description

Prucalopride, a highly selective 5-HT4 receptor agonist, accelerates gastrointestinal transit which may reduce severity of ileus. Furthermore, there is no report of serious cardiac and neurological side effects. We aim to evaluate the efficacy of prucalopride as a prokinetic of choice on paralytic ileus in critically ill patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04190173
Study type Interventional
Source Prince of Songkla University
Contact Panu Wetwittayakhlang, Dr.
Phone 66867725277
Email wet.panu@gmail.com
Status Recruiting
Phase Phase 3
Start date July 1, 2017
Completion date February 15, 2020
View Details
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