Clinical Trials Logo
  1. Home
  2. Critically Ill
  3. NCT02001207
  4. Details
NCT02001207 Clinical Trial

Salivary Cortisol in Intensive Care Unit

Critically Ill Clinical Trial

Official title:
Association of Salivary Cortisol Levels and Outcome of Critically Ill Patients in the Intensive Care Unit

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02001207
Other study ID # H-1304-072-482
Secondary ID
Status Recruiting
Phase N/A
First received November 27, 2013
Last updated November 18, 2014
Start date July 2013

Study information
Verified date December 2013
Source Seoul National University Hospital
Contact Jinwoo Lee, M.D.
Email realrain7@gmail.com
Is FDA regulated No
Health authority South Korea: Institutional Review Board
Study type Observational

Clinical Trial Summary

In critical illness, patients are highly stressed and should have elevated cortisol (stress hormone) secretion to adapt to stress. Dysfunction of this system is referred to as critical illness-related corticosteroid insufficiency. Free cortisol (unbound form) which is mainly responsible for its physiologic function is difficult to measure. We hypothesized that the salivary cortisol, which can be obtained by noninvasive methods, can more accurately evaluate adrenal function of critically ill patients.

Recruitment information / eligibility
Status Recruiting
Enrollment 90
Est. completion date
Est. primary completion date June 2015
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- patients who agreed to participate

Exclusion Criteria:

- Known adrenal or pituitary disease

- oral bleeding

- currently on systemic or inhaled corticosteroids

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Other:
• Salivary cortisol test

Locations
Country Name City State
Korea, Republic of Seoul National University Hospital Seoul

Sponsors (1)
Lead Sponsor Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary Overall mortality 28 days Yes
Secondary ICU days 28 days Yes
Secondary ventilator-free days 28 days Yes
See also
  Status Clinical Trial Phase
Recruiting NCT05539521 - Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Critically Ill Patients With Deep Sedation Phase 2
Recruiting NCT04776486 - Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance N/A
Completed NCT05766319 - The ICU-recover Box, Using Smart Technology for Monitoring Health Status After ICU Admission N/A
Recruiting NCT03231540 - The PREServation of MUScle Function in Critically Ill Patients (PRESMUS) N/A
Completed NCT02286869 - Cardioventilatory Coupling in Critically Ill Patients N/A
Completed NCT01434823 - 24 Hour Intensivist Coverage in the Medical Intensive Care Unit N/A
Active, not recruiting NCT01142570 - Effect of Enteral Nutrition Enriched in Protein and Based on Indirect Calorimetry Measurement in Chronically Critically Ill Patients N/A
Completed NCT01167595 - Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients N/A
Completed NCT01293708 - Realities, Expectations and Attitudes to Life Support Technologies in Intensive Care for Octogenarians:
Not yet recruiting NCT00916591 - Prokinetic Drugs and Enteral Nutrition N/A
Recruiting NCT00654797 - Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2 Phase 2
Withdrawn NCT00178321 - Improving Sleep in the Pediatric Intensive Care Unit N/A
Completed NCT01168128 - PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study N/A
Completed NCT02447692 - Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study N/A
Recruiting NCT04582760 - Early Mobilization in Ventilated sEpsis & Acute Respiratory Failure Study N/A
Not yet recruiting NCT05961631 - Bio-electrical Impedance Analysis Derived Parameters for Evaluating Fluid Accumulation
Completed NCT03276650 - Admission of Adult-onset Still Disease Patients in the ICU
Completed NCT03922113 - Muscle Function After Intensive Care
Recruiting NCT05055830 - Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
Recruiting NCT06027008 - Mechanical Insufflation-Exsufflation (Cough Assist) in Critically Ill Adults N/A