Critically Ill Clinical Trial
Official title:
Towards RECOVER - Rehabilitation and Recovery in Survivors of Critical Illness. Long-Term Outcomes and Needs Assessment in ICU Survivors of Prolonged Mechanical Ventilation and Their Caregivers
Advances in critical care medicine have dramatically improved the survival of critically ill
patients requiring prolonged mechanical ventilation. However, there are no systematic
follow-up, rehabilitation, or psychoeducational interventions for these vulnerable patients
or their family caregivers who contribute to survivor recovery and rehabilitation. Major
barriers to developing these programs for survivors of prolonged mechanical ventilation and
their caregivers include the following:
1. There is inadequate information about the determinants of long-term functional outcomes
for a diverse group of survivors of prolonged mechanical ventilation.
2. There is inadequate information about the needs of survivors of prolonged mechanical
ventilation and their family caregivers across the trajectory of illness (i.e., from
the ICU to the community).
3. There is a poor understanding of the development of ICU-acquired muscle injury.
Towards RECOVER is the very first study to identify survivors of prolonged mechanical
ventilation who are at-risk for poor functional outcomes, to identify elements of the
care-giving situation that put caregivers at risk for poor quality of life and mental
health, to catalogue the rehabilitative needs of patients and family caregivers across the
illness trajectory, and to evaluate the mechanism of critical illness associated muscle
injury.
The RECOVER Program consists of Four Phases:
- Phase I: Towards RECOVER
- Phase II: RECOVER development and pilot testing
- Phase III: RECOVER randomized controlled trial
- Phase IV: Long-term implementation of RECOVER
n/a
Observational Model: Cohort, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05539521 -
Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Critically Ill Patients With Deep Sedation
|
Phase 2 | |
Recruiting |
NCT04776486 -
Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance
|
N/A | |
Completed |
NCT05766319 -
The ICU-recover Box, Using Smart Technology for Monitoring Health Status After ICU Admission
|
N/A | |
Recruiting |
NCT03231540 -
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS)
|
N/A | |
Completed |
NCT02286869 -
Cardioventilatory Coupling in Critically Ill Patients
|
N/A | |
Completed |
NCT01434823 -
24 Hour Intensivist Coverage in the Medical Intensive Care Unit
|
N/A | |
Active, not recruiting |
NCT01142570 -
Effect of Enteral Nutrition Enriched in Protein and Based on Indirect Calorimetry Measurement in Chronically Critically Ill Patients
|
N/A | |
Completed |
NCT01167595 -
Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
|
N/A | |
Completed |
NCT01293708 -
Realities, Expectations and Attitudes to Life Support Technologies in Intensive Care for Octogenarians:
|
||
Not yet recruiting |
NCT00916591 -
Prokinetic Drugs and Enteral Nutrition
|
N/A | |
Recruiting |
NCT00654797 -
Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2
|
Phase 2 | |
Withdrawn |
NCT00178321 -
Improving Sleep in the Pediatric Intensive Care Unit
|
N/A | |
Completed |
NCT01168128 -
PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study
|
N/A | |
Completed |
NCT02447692 -
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study
|
N/A | |
Recruiting |
NCT04582760 -
Early Mobilization in Ventilated sEpsis & Acute Respiratory Failure Study
|
N/A | |
Not yet recruiting |
NCT05961631 -
Bio-electrical Impedance Analysis Derived Parameters for Evaluating Fluid Accumulation
|
||
Completed |
NCT03276650 -
Admission of Adult-onset Still Disease Patients in the ICU
|
||
Completed |
NCT03922113 -
Muscle Function After Intensive Care
|
||
Recruiting |
NCT05055830 -
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
|
||
Recruiting |
NCT06027008 -
Mechanical Insufflation-Exsufflation (Cough Assist) in Critically Ill Adults
|
N/A |