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Critically Ill Patients clinical trials

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NCT ID: NCT05790915 Completed - Clinical trials for Critically Ill Patients

Impact of Interventions on Admission SOFA Score on Clinical Outcomes of Critically Ill Patients

Start date: August 1, 2023
Phase:
Study type: Observational

Introduction: The SOFA score (Sequential Organ Function Assessment) and its derived measures, such as the Delta SOFA, are used worldwide to determine the severity and prognosis of critically ill patients. Objectives: The primary objective of this study was to assess the impact of standardized interventions on the six organ dysfunctions of SOFA score on outcomes of critically ill patients through the 48-hour delta SOFA with evaluation of the effectiveness of the interventions performed. Result will be correlated with the 28-day mortality. The secondary outcome measures comprised the evaluation of standardized interventions on ICU and hospital length of stay; vasopressor-free and ventilator-free days within the 28 days following ICU admission, through the effectiveness of interventions performed Uni and multivariate statistical analysis will be used to determine organ failures associated to outcome.

NCT ID: NCT04980274 Completed - Clinical trials for Critically Ill Patients

Impact of Admission SOFA Score and 48-hour Delta SOFA on Clinical Outcomes in Critically Ill Patients

Start date: January 1, 2020
Phase:
Study type: Observational

Organ dysfunctions are associated with high morbidity and mortality. The SOFA (Sequential Organ Failure Assessment) score developed by Vincent et al. sequentially assesses the presence and severity of dysfunctions in six organ systems: respiratory, cardiovascular, coagulation, hepatic, neurological and renal. Although the SOFA score was created to quantify organ dysfunctions, the obvious relationship between organ dysfunctions and mortality has been widely documented. Dynamic measurements of the SOFA score assess response to treatment and can be used to search for perpetuating sources of severity and reassess the treatment plan. The primary objective of this study will be to assess the impact of an admission SOFA score equal to or greater than 2 and subsequent interventions on outcomes related to the 48-hour delta SOFA on ICU and hospital mortality, length of stay in the ICU, duration of mechanical ventilation, time of vasoactive drug use. Patients will be divided into three groups: those who did not trigger the SOFA trigger on admission to the ICU (Group 1), those who triggered the SOFA trigger and improved on the third day (Group 2) and, finally, those who triggered the SOFA trigger and worsened on the third day (Group 3).

NCT ID: NCT04252027 Completed - Clinical trials for Critically Ill Patients

Therapeutic Drug Monitoring of Fluconazole in Critically Ill Patients

Start date: April 23, 2019
Phase:
Study type: Observational

This prospective study will research the exposure and its variability to fluconazole after longitudinal administration in critically ill patients

NCT ID: NCT03469882 Completed - Clinical trials for Critically Ill Patients

High Protein Intake and Early Exercise in Adult Intensive Care Patients

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

This study analyse the impact of high protein intake associated to early programed exercise on functional outcomes of adult intensive care patients.

NCT ID: NCT03205592 Completed - Clinical trials for Critically Ill Patients

Ultrasound Assessment of Residual Gastric Content in Critically Ill Patients

GastrICU
Start date: July 3, 2017
Phase:
Study type: Observational

This prospective observational study aims to assess whether ultrasound assessment of gastric content may be useful for the monitoring of the gastric residual content in critically ill patients

NCT ID: NCT02198950 Completed - Clinical trials for Critically Ill Patients

Combined Determination of sTREM-1, PCT and CD64 in Diagnosing Sepsis

Start date: November 2009
Phase:
Study type: Observational

The purpose of this study is to determine wether the combined measurement of the soluble form of TREM-1, PCT and the determination of neutrophils CD64 expression could diagnose sepsis in critically ill patients.

NCT ID: NCT01963013 Completed - Clinical trials for Critically Ill Patients

Non-returning Catheter Valve for Reducing CAUTI

Start date: June 2012
Phase: N/A
Study type: Interventional

This study was to determine efficacy of the non-returning catheter valve for reducing catheter associated urinary tract infection compared with conventional urine bag in critically ill patients.

NCT ID: NCT01794468 Completed - Clinical trials for Critically Ill Patients

A New Monitor to Measure Dermal Blood Flow in Critically Ill Patients: a Preliminary Study

MDBF-CIP
Start date: June 2003
Phase: N/A
Study type: Interventional

Background: Conditions of reduced perfusion are characterized by redistribution of blood flow away from the skin to more vital organs. Study Objectives: To assess the efficacy of a non-invasive, dermal blood flow (DBF) monitor in detecting changes in perfusion in critically ill patients. Preliminary Study Study Population: critically ill patients in a general ICU

NCT ID: NCT01411553 Completed - Clinical trials for Critically Ill Patients

ECG Leadwires: Disposable Versus Cleaned, Reusable

ECG-LW
Start date: September 2011
Phase: N/A
Study type: Interventional

Null hypothesis: (1) there is no difference in rates of ICU-acquired infection based on using disposable or cleaned, reusable ECG leadwires and (2) In cardiac surgical telemetry floors, there is no difference in false or nuisance sightings or crisis calls based on using disposable or cleaned, reusable ECG leadwires.

NCT ID: NCT01227148 Completed - Clinical trials for Critically Ill Patients

Influence of Tightly Glucose Control on Hyperglycemic Toxicity and Protein Catabolism in Critically Ill Patients

Start date: April 2006
Phase: Phase 3
Study type: Interventional

To compare the differences of urinary nitrogen excretion, nitrogen balance and clinical outcomes between tightly insulin therapy and conventional insulin therapy in the ICU.