Clinical Trials Logo

Clinical Trial Summary

This will be a randomized, placebo-controlled, parallel group, multicenter, Phase III study.The study aims to evaluate the Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects with Critical Limb Ischemia (CLI) with Minor Tissue Loss (Rutherford Category 5) who are Unsuitable for Revascularization.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03006770
Study type Interventional
Source Pluristem Ltd.
Contact
Status Active, not recruiting
Phase Phase 3
Start date May 22, 2017
Completion date March 2021

See also
  Status Clinical Trial Phase
Terminated NCT02287974 - Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin Phase 1/Phase 2
Completed NCT00987363 - Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no Revascularization Phase 1/Phase 2
Not yet recruiting NCT02538978 - Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System Phase 3
Completed NCT01408381 - Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI). Phase 2
Active, not recruiting NCT05208905 - LIFE-BTK PK Sub-study N/A
Recruiting NCT04849325 - IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease N/A
Completed NCT01257776 - Human Adipose Derived Mesenchymal Stem Cells for Critical Limb Ischemia (CLI) in Diabetic Patients Phase 1/Phase 2
Active, not recruiting NCT04227899 - LIFE-BTK Randomized Controlled Trial N/A
Terminated NCT03111238 - The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DM Phase 3
Terminated NCT03174522 - The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM Phase 3
Completed NCT01386216 - Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical Limb Ischemia (CLI) Phase 1
Available NCT03886506 - Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization
Available NCT03746899 - Expanded Access for Treatment Use of PLX-PAD in Critical Limb Ischemia (CLI)