Intensive Care Unit Activity in France From the National Database Between 2013 and 2019

Critical Illness Clinical Trial

— ICU_ACTIVITY  

Official title:

Intensive Care Unit Activity in France From the National Database Between 2013 and 2019: More Critically Ill Patients, Shorter Stay and Lower Mortality Rate

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05353023
• Other study ID #: LOCAL/2022/JYL-01
• Status: Completed
• Start date: January 1, 2013
• Est. completion date: December 31, 2019

Study information

• Verified date: April 2022
• Source: Centre Hospitalier Universitaire de Nimes
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Using data from the French National Uniform Hospital Discharge Database (systematically collecting administrative and medical information related to all hospitalized patients in France for care reimbursement purposes), the present study retrospectively assesses the activity of the French Intensive Care Unit (ICU)(1,594,801 ICU admissions):

• In-ICU and in-hospital mortality rates

• Length of stay in ICU and hospital

• Mortality-associated factors during the study period.

• Number of organ failures

• Bed occupancy,

• Regional variations in previous indicators

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1594801
• Est. completion date: December 31, 2019
• Est. primary completion date: December 31, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

All adults patients admitted in French ICU between January 1st, 2013, to December 31st, 2019

Related Conditions & MeSH terms

• Critical Illness
• Intensive Care Unit

Locations

Country	Name	City	State
France	Intensive care Unit CHU Nîmes	Nîmes

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Nimes

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Evolution in mortality rate	evolution of the mortality rate of ICU patients over the study period (2013-19)	from January 1st, 2013, to December 31st, 2019
Primary	Evolution in organ failure rate	evolution of the organ failure rate of ICU patients over the study period (2013-19)	from January 1st, 2013, to December 31st, 2019
Primary	Evolution in ICU stay	evolution of the ICU stay of ICU patients over the study period (2013-19)	from January 1st, 2013, to December 31st, 2019
Primary	Evolution in SAPS (Simplified Acute Physiology Score) II score at admission	evolution of the SAPS II score at admission of ICU patients over the study period (2013-19)	from January 1st, 2013, to December 31st, 2019
Primary	Evolution in age at admission	evolution of the age at admission of ICU patients over the study period (2013-19)	from January 1st, 2013, to December 31st, 2019
Primary	Evolution in sex ratio	evolution of the sex ratio of ICU patients over the study period (2013-19)	from January 1st, 2013, to December 31st, 2019
Secondary	Proportion of patients admitted in ICU with at least 2 different organ failures	evolution of the proportion of patients admitted in ICU with at least 2 different organ failures corresponding to the definition of ICU in France.	from January 1st, 2013, to December 31st, 2019
Secondary	- Proportion of patients admitted in ICU with a SAPS II score over 15 and with a specific ICU supportive therapy	Evolution of the proportion of patients admitted in ICU with a SAPS II score over 15 and with a specific ICU supportive therapy leading to a reimbursement by the French national health insurance.	from January 1st, 2013, to December 31st, 2019
Secondary	Factors Associated with in-ICU mortality	Effect of year-time on in-ICU mortality	from January 1st, 2013, to December 31st, 2019
Secondary	Regional variations	Evolution and potential differences between French regions in admission level	from January 1st, 2013, to December 31st, 2019