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A Trial of Enteral Colostrum on Clinical Outcomes in Critically Ill Patients

Critical Illness Clinical Trial

Official title:
Effects of Colostrum Supplement on Inflammatory and Growth Factors, Immune System Function and Clinical Outcomes in Hospitalized Patients With Enteral Feeding in Intensive Care Unit

Clinical Trial Summary

Enteral administration of immune-modulating nutrients such as glutamine, omega-3 fatty acids, selenium, and antioxidants has been suggested to reduce infections and improve recovery from critical illness. However, the effects of colostrum on clinical outcomes in critical ill patients has not been investigated. In current trial, intensive care unit patients with enteral feeding will receive either enteral colostrum or maltodextrin as placebo.

Clinical Trial Description

A randomized, double blind, controlled trial will be conducted in general intensive care unit (ICU) in Tehran, Iran. After a full review of the inclusion and exclusion criteria and explanation of the risks and benefits of the study, written consent form will be completed. Intervention patients will be received 20 g/day of colostrum along with enteral formula and control patients will be received maltodextrin along with enteral formula. Patients will be assessed for occurrence of new infection, organ failure, duration of stay in ICU, 28 days and 6 months mortality and inflammatory and immune markers. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03019250
Study type Interventional
Source National Nutrition and Food Technology Institute
Contact
Status Completed
Phase N/A
Start date January 15, 2017
Completion date November 7, 2018
View Details
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