Tight Glycemic Control With Intensive Insulin Therapy in PICU

Status Active, not recruiting

Clinical Trial Summary

In a previous study, the investigators showed that tight blood glucose control with insulin during intensive care reduced morbidity and mortality in adult intensive care patients. Whether this intervention also improves prognosis of pediatric intensive care patients remains unknown. The current prospective, randomized, controlled study will asses the impact of intensive insulin therapy on outcome of patients in a pediatric intensive care unit. On admission patients will be randomly assigned to either strict normalization of blood glucose according age adjusted values or the conventional approach, in which insulin infusion is initiated only when blood glucose exceeds 215 mg/dl to maintain blood glucose levels between 180-200 mg/dl.

Clinical Trial Description

Study type: Interventional study Study design: single centre, prospective, randomized, active control, parallel assignment, efficacy study ;

Study Design

Related Conditions & MeSH terms

Critical Illness

Clinical Trial Details

NCT number	NCT00214916
Study type	Interventional
Source	KU Leuven
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	October 2004
Completion date	June 2023

View Details

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