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Critical Illness Sepsis, Severe clinical trials

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NCT ID: NCT04850443 Withdrawn - Clinical trials for Critical Illness Sepsis, Severe

Treatment of IL-6 and Its Receptor Antagonists in Children's Severe Sepsis.

Start date: September 1, 2022
Phase:
Study type: Observational

In severe infective patients who survive the initial inflammatory storm, the immune response often evolves toward a state of immunosuppression, which contributes to increased mortality and severe secondary hospital-acquired infections. However, the role of IL-6 and its receptor antagonists in patients with severe sepsis and septic shock is discussed controversially. To date, the efficacy and safety of IL-6 and its receptor antagonists in children with severe infection is not fully evaluated.