Sonographic Evaluation of Diaphragmatic Function in Critical Care Patients With Use of Non Invasive Ventilation

Critical Care Clinical Trial

— ECHODIA  

Official title:

Sonographic Evaluation of Diaphragmatic Function in Critical Care Patients With Use of Non Invasive Ventilation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02380547
• Other study ID #: 5957
• Status: Completed
• First received: February 23, 2015
• Last updated: March 21, 2018
• Start date: June 19, 2015
• Est. completion date: July 15, 2016

Study information

• Verified date: March 2018
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Usefulness of non invasive ventilation in patients extubated after more than 48 hours of invasive ventilation is still in debate except for specific patients (chronic pulmonary disease and chronic heart failure).

Many experimental and clinical studies have shown that diaphragmatic function is depressed by mechanical ventilation in intubated patients.

The investigators will test the hypothesis that non invasive ventilation after extubation may improve diaphragmatic function

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Est. completion date: July 15, 2016
• Est. primary completion date: July 15, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patient extubated after at least 48 hours of invasive ventilation

• Requiring non invasive ventilation

• Consent of patient

Exclusion Criteria:

• Diaphragmatic paralysis

• Neuromuscular disease

• significant pleural effusion

• atelectasis requiring bronchoscopy

• abdominal hypertension

Related Conditions & MeSH terms

• Critical Care
• Invasive Mechanical Ventilation

Intervention

Other:
• Sonographic diaphragmatic measurements

Locations

Country	Name	City	State
France	Service d'anesthésie- réanimation chirurgicale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Diaphragmatic excursion		Before the first NIV session
Primary	Diaphragmatic thickening		Before the first NIV session
Primary	Diaphragmatic excursion		After the first NIV session
Primary	Diaphragmatic thickening		After the first NIV session
Primary	Diaphragmatic excursion		After 24 h of NIV use
Primary	Diaphragmatic thickening		After 24 h of NIV use