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Critical Care clinical trials

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NCT ID: NCT03920501 Active, not recruiting - Critical Care Clinical Trials

Comparison of Tele-Critical Care Versus Usual Care On ICU Performance (TELESCOPE)

TELESCOPE
Start date: August 5, 2019
Phase: N/A
Study type: Interventional

TELESCOPE will be a cluster randomized clinical trial to ascertain whether the use of an intervention including multidisciplinary round with a board certified physician through tele-critical care and periodic meetings to discuss strategies to improve quality indicators can reduce ICU length of stay of patients admitted to intensive care units (ICUs).

NCT ID: NCT03874923 Active, not recruiting - Critical Care Clinical Trials

Comparison of 250 ml Versus 500 ml of Fluid Challenge

KOBIAS
Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The objective of fluid challenge is to increase oxygen delivery (DO2) in order to improve/restore tissue oxygen consumption (VO2). However the fluid challenge volume to administer stills in debate, some studies recommend to administer 250 mL. Previous studies suggested that 500 mL of fluid challenge administration may improve cardiac output and oxygen delivery. The relation between the amount of fluid expansion and oxygen delivery and oxygen consumption was not yet been studied in a randomized study in critical care patients. This is the purpose of this study.

NCT ID: NCT03666286 Active, not recruiting - Rehabilitation Clinical Trials

Prospective Registry of Mobilization-, Routine- and Outcome Data of Intensive Care Patients

MOBDB
Start date: February 1, 2017
Phase:
Study type: Observational [Patient Registry]

Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.

NCT ID: NCT03540732 Active, not recruiting - Critical Care Clinical Trials

Feeding With Indirect Calorimetry and Cycling in the Elderly

FICE
Start date: November 6, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of early exercise by cycle ergometry and early targeted feeding in reducing muscle atrophy and improve functional outcomes in the older critically ill patient.

NCT ID: NCT03471247 Active, not recruiting - Respiratory Failure Clinical Trials

CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients

CYCLE
Start date: October 15, 2018
Phase: N/A
Study type: Interventional

Patients who survive critical illness usually experience long-lasting physical and psychological impairments, which are often debilitating. Rehabilitation interventions started in the ICU may reduce this morbidity. In-bed cycling, which uses a special bicycle that attaches to the hospital bed, allows critically ill patients who are mechanically ventilated (MV) to gently exercise their legs while in the ICU. The main goal of this study is to determine whether critically ill MV adults recover faster if they receive early in-bed cycling than if they do not. Another objective is to determine whether in-bed cycling is a cost-effective intervention. 360 patients admitted to the ICU and receiving MV will be enrolled in the study. Following informed consent, patients will be randomized to either (1) early in-bed cycling and routine physiotherapy or (2) routine physiotherapy alone. Patients' strength and physical function will be measured throughout the study. If early in-bed cycling during critical illness improves short-term physical and functional outcomes, it could accelerate recovery and reduce long-term disability in ICU survivors.

NCT ID: NCT03090867 Active, not recruiting - Critical Care Clinical Trials

Participation of Relative or Surrogate in the Patient's Care in Reanimation

PARTICIPATE
Start date: November 16, 2017
Phase: N/A
Study type: Interventional

ICUs have always perceived by the public has a very technical unit with a restricted and/or forbidden access. Physical alteration of the patient, seeing the patient sedated, the large numbers of devices, the alarms and an uncertain prognosis. All this factors can be perceived by people close to the patient as a source of stress. In the literature, numerous studies have shown that families develop anxiety and depression symptoms while their loved one is hospitalized in the ICU. French intensive care societies thought of ways to prevent or diminish these symptoms. The 6th consensus conference on " Live better in the ICU " recommends: effective and adapted information, large visiting hours to reach an unrestricted access and family participation in care. The unit has taken this path to improve patient and family centered care by: creating a welcome leaflet, a room dedicated to meetings with families and an ICU open 24/7bto families, with the possibility for children to visit their parents. Hence, spontaneously, relatives have expressed the wish to participate to certain care and when participating, expressed their satisfaction. This observation and testimonies from family members and patients led us to think about the impact of participation of care. Two major French studies have shown contradictory outcomes: 16% of families would have been willing to participate in the first study against 97% in the second one. These studies were survey done after the ICU discharge. No study today has assessed the actual impact of family participation in care. The aim of this clinical trial is to diminish anxiety and depression symptoms. By participating in care, relatives can develop or strengthen a relationship of trust with caregivers. It could contribute also to a better understanding of the plan of care and an easier context to announce negative outcomes.

NCT ID: NCT02963558 Active, not recruiting - Critical Illness Clinical Trials

A Study Promoting Critical Illness Recovery in the Elderly

ASPIRE
Start date: May 30, 2017
Phase: N/A
Study type: Interventional

This proposal will test the hypothesis that EARLY application of a novel early rehabilitation therapy in critically ill patients will improve functional outcomes, and change the functional trajectory of this population. A pilot study of early mobilization with a cycle ergometer will be performed and translate into humans the pre-clinical mechanisms that may mediate the effects of early mobility. A second phase of the study was added in September 2019, which will focus on clinical outcomes.