Cranial Soft Tissue Clinical Trial
Official title:
Validierung Der Bestimmung Der Gewebedicke Mit Hilfe Von Licht im Infrarotbereich
The study is intended to verify a newly developed method to measure the thickness of cranial
soft tissue. In the study, a high-resolution MRI scan is used as ground truth for a laser
scan of the forehead. The laser scan is acquired point by point with a prototype scanning
unit developed at the University of Luebeck's Institute for Robotics.
The measured tissue thickness using the near-infrared scanning approach is validated against
the ground truth obtained by the MRI scan. The average accuracy of the reconstruction method
is then computed over all subjects from the individual study arms.
The required laser intensity and exposure time as well as the achieved measurement accuracy
is evaluated with respect to the different skin types of the test subjects. Correlation
between these features and the skin type according to the Fitzpatrick scale will be
computed.
For 1/3 of the subjects, the laser and MRI scans are repeated after 2 and 8 weeks. The
results of the scans are compared and time dependency is analysed.
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Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science