Cow's Milk Allergy Clinical Trial
Official title:
Effect of Therapy With Aminoacid Based Formula Versus Hydrolyzed Whey Proteins in Children With Cow's Milk Allergy
Cow's milk allergy is an immunologically mediated adverse reaction to milk proteins. In
industrialized countries there is an incidence of 2-3% in children younger than 2 years.
Cow's milk allergy may present with different clinical pictures and symptoms often
nonspecific. Among the most common are certainly food refusal and failure to thrive until
frameworks frank malnutrition. It was also noted that the cow's milk allergy can have a
negative impact on the quality of life of the patient and his family.
The treatment of this condition provides the setting of a diet that is free of the allergen
to the base of the adverse reaction.
There are some types of formulas for the treatment of this condition. The formulas based on
amino acids are currently used in all cases non-responsive to treatment with the above
formulas or in all those characterized by severe allergic reactions. Being made from amino
acids such formulas are by definition non-allergenic. They have also proven to ensure a
rapid resolution of symptoms favoring a resumption of growth, nutritional status, as well as
lead to a rapid improvement in the quality of life of the patient and his family. However,
the studies currently available to us concerning the effects of nutritional formulas based
on amino acids affect short observation periods (usually less than 6 months) and were
directed to a comparison only with hydrolysates of whey protein or casein and not with
healthy subjects. To date thus lack consistent data on the nutritional effects in the medium
to long term.
n/a
Observational Model: Cohort, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02738060 -
The Effect of Baked Milk on Cow's Milk Allergy
|
Phase 2 | |
Recruiting |
NCT02149134 -
Evaluation of the Efficacy of a New Infant Formula in Subjects With Cow's Milk Allergy
|
Phase 2 | |
Recruiting |
NCT01891916 -
Effect Of Lactobacillus GG on Atopic March
|
N/A | |
Completed |
NCT01634490 -
Effects of Different Dietary Regimens on Tolerance Acquisition in Children With Cow's Milk Allergy
|
N/A | |
Completed |
NCT01622426 -
Tolerance to a New Free Amino Acid-based Formula in Children With IgE or Non-IgE-mediated Cow's Milk Allergy
|
N/A | |
Completed |
NCT02466035 -
Epigenetic Effects Involved in Children With Cow's Milk Allergy (EPICMA)
|
N/A | |
Completed |
NCT04330092 -
Diagnosis of Cow's Milk Protein Allergy
|
||
Not yet recruiting |
NCT02081651 -
Parmigiano-Reggiano Cheese as a Possible Strategy to Acquire Oral Tolerance in Children With Cow's Milk Allergy
|
Phase 3 | |
Completed |
NCT03462030 -
Baked Milk Oral Immunotherapy for Cow's Milk Allergy
|
Phase 2 | |
Completed |
NCT02465905 -
Oral Immunotherapy in Cow's Milk Allergy (CMA) in Children : "Petit Lait" Study
|
N/A | |
Suspended |
NCT05731206 -
Hypoallergenicity of a Hydrolyzed Protein Infant Formula
|
N/A | |
Not yet recruiting |
NCT06456541 -
Infant Formula in Infants and Children With Cow's Milk Allergy
|
N/A | |
Recruiting |
NCT02062476 -
Epigenetic Effects Elicited By Lactobacillus GG In Children With Cow's Milk Allergy
|
Phase 2 | |
Completed |
NCT01589731 -
Polymerized Beta-lactoglobulin Comparative Immunoreactivity
|
N/A | |
Terminated |
NCT02405923 -
Growth, Safety and Tolerance of a Rice Protein Hydrolysate Formula in Infants With Cow's Milk Protein Allergy
|
N/A | |
Terminated |
NCT04910373 -
Extensively Hydrolyzed Infant Formula in Infants and Children With Cow's Milk Allergy
|
N/A | |
Recruiting |
NCT01968278 -
Use of Baked Milk in Oral Immunotherapy for Severe IgE-mediated Cow's Milk Protein Allergic Patients
|
N/A | |
Withdrawn |
NCT01470768 -
Evaluation of Fatty Acid Levels and Growth in Infants Fed Amino Acid Based (AA) Formulas
|
N/A | |
Recruiting |
NCT05883384 -
Validity of Cow's Milk-related Symptom Score Among Children Suspected to Have Cow's Milk Protein Alergy
|
||
Completed |
NCT01901380 -
Cow's Milk Allergy and Functional Gastrointestinal Disorders
|
N/A |