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Microbiota as Potential Target for Food Allergy — MATFA  

Cow Milk Allergy Clinical Trial

Official title:
Microbiota as Potential Target for Innovative Preventive and Therapeutic Strategies for Food Allergy

Clinical Trial Summary

Food allergy (FA) derives from a dysregulation of oral tolerance mechanisms. Studies suggest a crucial role for enteric microflora in oral tolerance development. An altered composition of intestinal microflora results in an unbalanced local and systemic immune response to food allergens. There are qualitative and quantitative differences in gut microbiota composition in children with food allergy. These findings support the concept that specific beneficial bacteria from human intestinal microflora, designated probiotics, could restore intestinal microflora homeostasis and prevent or treat FA.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02087930
Study type Observational
Source Federico II University
Contact
Status Recruiting
Phase
Start date March 2013
Completion date September 2020
View Details
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