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Clinical Trial Summary

Context: Therapeutic plasma exchange (TPE) is an extracorporeal blood purification technique that removes pathogenic substances (including antibodies) from plasma. This technique also combines an immunomodulatory effect. The impact on the anti-SARS-CoV-2 titer and the humoral and cellular response in the general population benefiting from an EFA program is not known at this time. The purpose of this study is to evaluate the evolution of anti-SARS-CoV-2 titer over time in vaccinated adult patients treated with TPE. Research question and associated variables: Prospective non-drug interventional study on the possible variation of anti-SARS-CoV-2 antibody titer in adult patients regularly treated with therapeutic plasma exchange. Study population: any adult patient vaccinated against SARS-CoV-2 (any type of vaccine) and regularly receiving therapeutic plasma exchange in the adult hematology department of the Cliniques universitaires Saint Luc in Brussels, Belgium. Number of subjects expected to be enrolled: 10-15


Clinical Trial Description

Not provided ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05191394
Study type Interventional
Source Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Contact Cliniques U Saint-Luc, Pr
Phone +3227641708
Email [email protected]
Status Recruiting
Phase N/A
Start date September 8, 2021
Completion date February 1, 2022

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