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NCT ID: NCT04684446 Not yet recruiting - COVID-19 Clinical Trials

AstraZeneca Vax - Sputnik V Combination Study

Start date: March 30, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The objective is to evaluate the safety and immunogenicity of AZD1222 given in combination with (either before or after) rAd26-S, for the prevention of COVID 19 in adults ≥ 18 years of age.

NCT ID: NCT04649840 Enrolling by invitation - Covid19 Clinical Trials

Estimation of Dynamics of Humoral and Cellular Immunity in COVID-19 Patients

Start date: October 1, 2020
Phase:
Study type: Observational

The goal of the project: to study the dynamics of the humoral and cellular immunity in patients after pneumonia caused by the SARS-CoV-2 virus at different time intervals, in order to predict the duration of immune protection

NCT ID: NCT04644978 Recruiting - Mental Illness Clinical Trials

European Study on the Attitude of Psychiatrists Towards Their Patients

Eustigma
Start date: July 29, 2020
Phase:
Study type: Observational

Background: Many people think that people with mental disorders might be dangerous or unpredictable. These patients face various sources of disadvantages and experience discrimination on job interviews, in education, and housing. Mental health-related stigma (MHS) occurs not only within the public community, it is a growing issue among professionals as well. Aim: We designed a prospective, observational, multi-centre, international study of 35 European countries to investigate the MHS among medical specialists and trainees in the field of general adult and child and adolescent psychiatry. Methods: An internet-based, anonymous survey will measure the stigmatizing attitude by using the local version of the Opening Minds Stigma Scale for Health Care Providers. Presentation of the Results: The results of the research will be published in an international peer-reviewed journal. Furthermore, we will present the results on national and international conferences.

NCT ID: NCT04633564 Completed - NSCLC Stage IV Clinical Trials

MYL-1402O Compared With Avastin®, in Patients With Stage IV nsNSCLC

Start date: January 21, 2017
Phase: Phase 3
Study type: Interventional

Assess the Efficacy and Safety of MYL-1402O Compared with Avastin®, in the First-line Treatment of Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

NCT ID: NCT04608760 Enrolling by invitation - Acute Pancreatitis Clinical Trials

Prevention of Acute Pancreatitis After Endoscopic Interventions

Start date: August 1, 2020
Phase: Phase 1
Study type: Interventional

The aim of the study is to develop a method for the prevention of acute pancreatitis after minimally invasive interventions of the bile ducts using a drug regimen.

NCT ID: NCT04588935 Recruiting - Clinical trials for Women With Breast Cancer With a Morphologically Confirmed Diagnosis Before the Appointment of Anticancer Therapy

TO DEVELOP AND IMPLEMENT A METHOD FOR MEDICAL PREVENTION OF CARDIOVASCULAR DISEASES CAUSED BY COMPLEX TREATMENT OF PATIENTS WITH PRIMARY OPERATED BREAST CANCER

Start date: July 1, 2019
Phase: Phase 2
Study type: Interventional

Purpose of the study: to develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular complications

NCT ID: NCT04565990 Not yet recruiting - Clinical trials for Hypertension, Pulmonary

A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study

SOMBRERO
Start date: March 3, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the long-term safety of selexipag while providing continued selexipag treatment for participants who were previously enrolled in an Actelion-sponsored study with selexipag and who derived benefit from selexipag in indications for which a positive benefit-risk has been established.

NCT ID: NCT04564716 Active, not recruiting - Covid19 Clinical Trials

Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 in Belarus

Start date: September 28, 2020
Phase: Phase 3
Study type: Interventional

Randomized, double-blind (blinded for the trial subject and the study physician), placebo controlled, multi-center clinical trial in parallel assignment of efficacy, immunogenicity, and safety of the Gam-COVID-Vac combined vector vaccine against the SARS-CoV-2-induced coronavirus infection in adults in the SARS-СoV-2 infection prophylactic treatment.

NCT ID: NCT04549025 Recruiting - NSCLC Clinical Trials

Study of PD-1 Inhibitor JTX-4014 Alone and in Combination With Vopratelimab in Biomarker-selected Subjects With Metastatic NSCLC After One Prior Platinum-containing Regimen

SELECT
Start date: October 19, 2020
Phase: Phase 2
Study type: Interventional

This is a Phase 2, open-label study to evaluate PD-1 inhibitor JTX-4014 alone and in combination with vopratelimab, an ICOS agonist, in biomarker-selected adult subjects with metastatic NSCLC who are PD-1/PD-L1 inhibitor naïve and have progressed on a platinum based chemotherapy regimen.

NCT ID: NCT04542226 Completed - Clinical trials for Infections, Coronavirus

Observational Open Study of Polyoxidonium in Hospitalized Patients With COVID-19

Start date: March 31, 2020
Phase:
Study type: Observational

The study is designed as an open observational non-comparative study of Polyoxidonium®, lyophilizate for solution for injections and topical application, 12 mg in hospitalized patients with coronavirus disease (COVID-19).