Coughing Clinical Trial
Official title:
Effect of Single-dose Dexmedetomidine on Airway Reflex in Adult With Oral Intubation After Thyroidectomy
Coughing during emergence from general anaesthesia may lead to dangerous effects including
laryngospasm, detrimental haemodynamic changes. Post-thyroidectomy bleeding occurs in 1-4%
of patients, and severe coughing may cause bleeding. Dexmedetomidine, a potent α
adrenoreceptor agonist, is theoretically appropriate for reducing airway and haemodynamic
reflexes during emergence from anaesthesia.
In this study, we investigated whether intravenous single-dose dexmedetomidine at the end of
surgery reduces coughing during extubation after thyroidectomy.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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