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Corpora Cavernosa; Inflammation clinical trials

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NCT ID: NCT03463239 Not yet recruiting - Urologic Diseases Clinical Trials

Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora

Start date: January 2025
Phase: Phase 1
Study type: Interventional

The primary objective of this clinical trial is to evaluate the safety of autologous engineered corpora cavernosa + albuginea constructs for treatment of complex penile deformities. Autologous endothelial and smooth muscle cells obtained from enrolled subjects' corpora cavernosa biopsy sample, will be culture expanded in vitro and used to seed decellularized corpora cavernosa + albuginea obtained from cadaveric-donors to create autologous bioengineered corpora cavernosa/albuginea constructs for repair of damaged penile tissues.