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Convalescent Plasma to Stem Coronavirus (CSSC-001) — CSSC-001  

Coronavirus Clinical Trial

Official title:
Convalescent Plasma to Stem Coronavirus: A Randomized, Blinded Phase 2 Study Comparing the Efficacy and Safety Human Coronavirus Immune Plasma (HCIP) vs. Control (SARS-CoV-2 Non-immune Plasma) Among Adults Exposed to COVID-19

Clinical Trial Summary

Evaluate the efficacy of treatment with high-titer Anti- SARS-CoV-2 plasma versus control (SARS-CoV-2 non-immune plasma) in subjects exposed to Coronavirus disease (COVID-19) at day 28.

Clinical Trial Description

This randomized, controlled, double-blinded phase 2 trial will assess the efficacy and safety of Anti- SARS-CoV-2 convalescent plasma as prophylaxis following exposure to COVID-19 (as defined in the inclusion criteria). Adults 18 years of age and older with high risk exposure as defined by CDC may participate. A total of 500 eligible subjects will be randomized in a 1:1 ratio to receive either high titer anti-SARS-CoV-2 plasma or control (SARS-CoV-2 non-immune plasma). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04323800
Study type Interventional
Source Johns Hopkins University
Contact
Status Completed
Phase Phase 2
Start date June 10, 2020
Completion date June 22, 2021
View Details
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