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Clinical Trial Summary

COVID-19 has rapidly evolved into a generalized global pandemic. Post-exposure prophylaxis (PEP) against on COVID-19 was identified as an urgent research priority by the WHO, and lopinavir/ritonavir (LPV/r) is a promising candidate for both COVID-19 treatment and PEP, with a good safety profile and global availability. This is a cluster randomized controlled trial (RCT) of oral LPV/r as PEP against COVID-19, that will address the immediate need for preventive interventions, generate key data on COVID-19 transmission, and serve as a research platform for future vaccines and preventive agents.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04321174
Study type Interventional
Source Unity Health Toronto
Contact
Status Active, not recruiting
Phase Phase 3
Start date April 17, 2020
Completion date March 31, 2022

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