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Coronary Vessels clinical trials

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NCT ID: NCT05388357 Active, not recruiting - Coronary Vessels Clinical Trials

AI Quantitative Coronary Angiography Versus Optical Coherent Tomography Guidance for Coronary Stent Implantation

FLASH
Start date: October 4, 2022
Phase: N/A
Study type: Interventional

This study is to establish the primary hypothesis thatAI -QCA guided PCI is non-inferior to Optical coherence tomography-guided Percutaneous coronary intervention regarding minimal Stent area by Final OCT and Procedural MACE

NCT ID: NCT04414176 Recruiting - Coronary Vessels Clinical Trials

Iran- Premature Coronary Artery Disease

I-PAD
Start date: August 25, 2018
Phase:
Study type: Observational

This case-control study will be conducted all over the country (in Persian, Kurd, Azari, Arab, Lor, Bakhtiari, Baluch, Turkman, Qashqai, Gilak and in Muslims, Christians, Jewish, and Zoroastrian). the investigators intend to recruit patients (men 60≥ years of age and women 70≥ years of age) who underwent coronary angiography. Patients with coronary artery stenosis more than 75% (or left-main stenosis more than 50%) are defined as case group and patients with normal angiography are considered as the control group. at the same time, the prevalence of premature coronary artery disease in patients with positive angiography will be calculated.

NCT ID: NCT03401203 Completed - Coronary Vessels Clinical Trials

Debulking With Rotational Atherectomy Versus Balloon Angioplasty In Patients With In-stent Restenosis

ROTA-ISR
Start date: May 8, 2018
Phase: N/A
Study type: Interventional

This study is to establish the primary hypothesis that debulking with rotational atherectomy (RA) followed by balloon angioplasty (BA) is superior to BA alone for lesion preparation in patients with coronary in-stent restenosis (ISR) regarding angiography-measured in-segment minimal lumen area at 1 year.

NCT ID: NCT03394079 Active, not recruiting - Coronary Vessels Clinical Trials

Optical Coherence Tomography Versus Intravascular Ultrasound Guided Percutaneous Coronary Intervention

OCTIVUS
Start date: April 12, 2018
Phase: N/A
Study type: Interventional

The primary aim of this study is to compare the clinical efficacy and safety of OCT-guided(optical coherence tomography (OCT)-guided) and IVUS-guided(Intravascular ultrasound (IVUS)-guided) strategies in patients undergoing Percutaneous coronary intervention (PCI) with contemporary drug-eluting stents (DES) or drug-coated balloons (only for in-stent restenosis) for significant obstructive Coronary artery disease (CAD). The investigators hypothesize that OCT-guided PCI is non-inferior to IVUS-guided PCI with respect to primary end point of target-vessel failure (cardiac death, target-vessel myocardial infarction [MI], or ischemia-driven target-vessel revascularization [TVR]) at 1 year after randomization.

NCT ID: NCT00427232 Completed - Coronary Vessels Clinical Trials

Endothelin-Receptor Blockade in Coronary Heart Disease

Start date: May 2003
Phase: Phase 1
Study type: Interventional

Endothelin is a hormon that causes acute and chronic narrowing of heart vessels. The purpose of this study is to assess whether suppression of this activity by using two types of receptor antagonists can reduce this effect and thus improve blood supply of the heart muscle.