Coronary Microvascular Disease Clinical Trial
Official title:
Personalized Medicine Using Coronary Microvascular Function Measured in Patient With Percutaneous Coronary Intervention in Angina
The evidence demonstrating the importance of coronary microcirculation in the management of patients with coronary artery disease is growing. For example, in recent years, a number of studies have demonstrated that the presence of coronary microvascular disease (CMVD) contributes to increased cardiovascular morbidity and mortality independent of the extent and severity of coronary epicardial disease. The index of microcirculatory resistance (IMR) is an invasive index proposed for the diagnosis of CMVD. The ability of IMR to motivate therapeutic changes in order to subsequently reduce symptoms and improves the quality of life of our patients with stable coronary artery disease (CAD) was recently demonstrated. The prognostic value of IMR has also been shown in stable CAD with PCI. Thus, after optimal epicardial evaluation and if necessary revascularization according to FFR, IMR could represent a tool for personalized medicine adapted to the presence of severe CMVD. The aim of the study is to demonstrate a positive effect of personalized medicine on angina in patients with epicardial coronary network lesion assessment by FFR and with significant CMVD assessed by IMR.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06125392 -
Multicenter Registry on Microvascular Dysfunction - Searching a New Ach Spasm Definition
|
||
| Recruiting |
NCT05805462 -
The Euro-CRAFT Registry
|
||
| Terminated |
NCT04614467 -
A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction
|
Phase 2 | |
| Recruiting |
NCT04598997 -
Artificial Intelligence With DEep Learning on COROnary Microvascular Disease
|
||
| Completed |
NCT03104062 -
Effect of Ticagrelor and Clopidogrel on Coronary Microcirculation in Patients With Acute Myocardial Infarction
|
N/A | |
| Completed |
NCT04202172 -
Functional Assessment of the Infart-related Artery With Bioactive and Polymer-free Coronary Stents (The FUNCOMBO Trial)
|
Phase 4 | |
| Not yet recruiting |
NCT05793567 -
A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI)
|
||
| Completed |
NCT03523624 -
Factor XIII and Other Biomarkers in ST Segment Elevation Myocardial Infarction
|
||
| Completed |
NCT02045459 -
Microvascular Disease Exercise Trial
|
N/A | |
| Recruiting |
NCT05825339 -
Absolute Flow for Ischemia With No Obstructive Coronary Arteries
|
||
| Active, not recruiting |
NCT04005963 -
The Value of PET Quantitative Analysis of Coronary Physiology in Coronary Microvascular Disease
|
||
| Recruiting |
NCT05743140 -
A Clinical Study of Fundus OCTA for the Identification of CMD
|
||
| Recruiting |
NCT03064295 -
Whole-Heart Myocardial Blood Flow Quantification Using MRI
|
||
| Not yet recruiting |
NCT06212466 -
MCG as a Noninvasive Diagnostic Strategy for Suspected INOCA (MICRO2)
|
||
| Recruiting |
NCT03537586 -
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
|
N/A | |
| Recruiting |
NCT04960371 -
Effects of Anxiety on Coronary Microcirculatory Function in Hypertensive Patients
|
||
| Enrolling by invitation |
NCT05913999 -
Serial PET MPI in Patients Undergoing Cancer Treatment
|
||
| Recruiting |
NCT05810051 -
Exercise and Coronary Microvascular Disease
|
N/A | |
| Completed |
NCT05471739 -
Simultaneous Assessment of Coronary Microvascular Dysfunction and Ischemia With Non-obstructed Coronary Arteries With Intracoronary Electrocardiogram and Intracoronary Doppler
|
||
| Recruiting |
NCT04440761 -
Barts-MINOCA Registry
|