Warfarin and Coronary Calcification Project — WACC  

Coronary Calcification Clinical Trial

Official title: Warfarin and Coronary Calcification Project

Status Completed

Clinical Trial Summary

The purpose of the study is to assess whether the use of warfarin, a commonly used anticoagulation drug, is associated with increased amounts of coronary artery calcification. Studies in animals and preliminary but small retrospective studies in humans have suggested a possible link to increased tissue calcification with use of this drug. The researchers will investigate this by assessing the amount of calcification seen in the coronary arteries using a specialized computed tomography (CT) scan (electron-beam CT) and assessing to see if the amount is influenced by the amount of time a patient has been taking warfarin. The researchers will exclude patients with known coronary artery disease, chronic kidney disease or hyperparathyroidism.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Calcinosis
• Coronary Calcification

• NCT number: NCT00868712
• Study type: Observational
• Source: Walter Reed Army Medical Center
• Status: Completed
• Phase: N/A
• Start date: May 2004
• Completion date: January 2010