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Coronary Artery Stenosis clinical trials

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NCT ID: NCT05995002 Recruiting - Clinical trials for Coronary Artery Stenosis

Anthocyanin Intake on Cardiometabolic Biomarkers

Start date: August 21, 2023
Phase: N/A
Study type: Interventional

Flavonoids are one of the main groups of polyphenols. Anthocyanins, which are a subgroup of the flavonoid family, are found in a number of fruits and some vegetables. In epidemiological studies, high dietary intake of polyphenols has been associated with improvement of some cardiometabolic risk factors in high-risk individuals. Furthermore, in controlled studies, consumption of polyphenol-rich food sources or anthocyanin extract supplementation has improved some cardiometabolic factors. In the present study, the effect of diet enriched with anthocyanin-rich food sources on cardiometabolic factors will be studied in coronary artery disease patients.

NCT ID: NCT05935397 Recruiting - Clinical trials for Coronary Artery Disease

HanYang University Medical Center (HYUMC) Registry

HYUMC
Start date: January 1, 2012
Phase:
Study type: Observational [Patient Registry]

The HYUMC registry is a two-center, real-world registry of percutaneous coronary intervention in patients with coronary artery disease. From January 2012, PCI-treated patients from Hanyang University Seoul Hospitals and Hanyang University Guri Hospitals were enrolled in this registry. The aim of this registry is to examine the long-term clinical outcomes and identify predictors of adverse outcomes following percutaneous coronary intervention conducted at academic hospitals.

NCT ID: NCT05860400 Recruiting - Clinical trials for Coronary Artery Disease

Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study

Start date: May 17, 2023
Phase:
Study type: Observational [Patient Registry]

This is a self-controlled cohort study to evaluate the efficacy and safety of comprehensive treatment in patients with inflammation-associated rapidly-progressive coronary artery disease (IR-CAD) by comparing the study endpoints before treatment with those after treatment in the same group of patients.

NCT ID: NCT05757947 Recruiting - Clinical trials for Coronary Artery Disease

Study of the No-touch Saphenous Vein Graft

Start date: December 22, 2022
Phase: N/A
Study type: Interventional

Authors hypothesize that "no-touch" saphenous vein as I graft is superior over conventional "no-touch" saphenous vein as free graft in the incidence of graft patency.

NCT ID: NCT05606367 Recruiting - Clinical trials for Coronary Artery Stenosis

Coronary Non-slip Balloon Catheter in Patients With Coronary Artery Stenosis(CREST)

Start date: January 3, 2023
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, randomized controlled clinical investigation aiming to evaluate the safety and effectiveness of non-slip balloon catheter for the treatment of patients with coronary artery stenosis.

NCT ID: NCT05532605 Recruiting - Clinical trials for Coronary Artery Stenosis

Effects of Mindfulness Based Therapy on Illness and Depression in Cardiac Rehab Phase-i

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

A randomize controlled trial will be conducted at Punjab institute of cardiology hospital Lahore, through convenience sampling technique on 48 patients which will be allocated through simple random sampling through sealed opaque enveloped into group A and Group B. Pretreatment values of patients' blood pressure, RR, HR, will be recorded. And patient's perception of illness through Illness Perception Questionnaire (IPQ), PHQ9 for depression assessment and HRQOL for quality of life will be assessed before and after treatment. Group A will be treated with basic Phase-I cardiac rehabilitation. And Group B will be treated with basic Phase-I cardiac rehabilitation along with Mindfulness based therapy. Treatment evaluation will be done after 8 weeks. Data will be analyzed using SPSS software version 25. After assessing normality of data by Shapiro-Wilk test, it will be decided either parametric or non-parametric test will be use within a group or between two groups.

NCT ID: NCT05320185 Recruiting - Clinical trials for Coronary Artery Disease

Evaluation on the Effectiveness and Safety of RuiXin-CoronaryAI for Diagnosis of Coronary Artery Stenosis

Start date: July 28, 2021
Phase:
Study type: Observational

With the emergence of advanced technology to date in the artificial intelligence (AI), computer aided diagnosis has gradually gained its popularity in the field of healthcare. Particularly, in the clinical practice of coronary artery disease diagnosis, the application of AI could be of great implication in alleviating the shortage of medical sources. To evaluate the effectiveness and safety of the AI-based coronary CT angiographic analysis software (RuiXin-CoronaryAI) for diagnosis of coronary artery stenosis, a retrospective, multi-center, cross-over designed, blinded, sensitivity superiority and specificity non-inferiority clinical trial will be conducted.

NCT ID: NCT05133843 Recruiting - Clinical trials for Coronary Artery Stenosis

Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis

CHOICE-FR
Start date: September 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the current study is to assess complete coronary physiology (FFR, RFR, CFR, IMR, and CT-FFR) in TAVI candidates with intermediate coronary artery stenosis before and 6 months after TAVI. This aims to determine how TAVI affects coronary blood flow and coronary microcirculatory function after longer-term follow-up, and how these effects influence FFR and RFR values. In addition, it is aimed to correlate invasive functional testing (FFR and RFR) with non-invasive CT-FFR before and 6 months after TAVI.

NCT ID: NCT04893291 Recruiting - Clinical trials for Coronary Artery Disease

Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels

TRANSFORM II
Start date: November 16, 2021
Phase: N/A
Study type: Interventional

International, multicentric, prospective, investigator-driven, open-label, randomized (1:1) clinical trial to observe and evaluate the efficacy, of Magic Touch Sirolimus Coated Balloon (SCB) compared to one of the gold standard treatment for native vessel disease (everolimus-eluting stent, EES).

NCT ID: NCT04788186 Recruiting - Clinical trials for Coronary Artery Disease

Beta Blocker De-prescription Following Coronary Artery Bypass Graft Surgery (BEEFBURGER Trial).

BEEFBURGER
Start date: August 23, 2021
Phase: Phase 4
Study type: Interventional

Beta-blockers have the greatest cardiovascular impact in patients with reduced heart function/heart failure and in reducing the peri-operative risk of atrial fibrillation. In patients without these high-risk features treated with coronary artery bypass graft (CABG) surgery, their continued long-term role is unclear.