Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients

Coronary Artery Ectasia Clinical Trial

Official title:

Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05106530
• Other study ID #: Arrhythmias in CAE patients
• Status: Recruiting
• Start date: January 1, 2022
• Est. completion date: January 1, 2023

Study information

• Verified date: October 2021
• Source: Assiut University
• Contact: Mark M N Kamel, Resident
• Phone: +201274327737
• Email: markkamel1994[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The investigators thought to explore arrhythmias outcome - hidden arrhythmias, ECG features: Tp-Te interval and Tp-Te/QTc ratio, fQRS among patients with coronary artery ectasia as compared to normal coronary artery patients.

Description:

All patients will be subjected to:

A. Full history taking:

• Including age, sex, history of DM, HTN, dyslipidemia and Body surface area.

B. Holter monitoring for 24 hours:

• Heart rate variability

• Hidden arrhythmias

• Hidden ischemia by monitoring ST segment changes

C. Twelve lead ECG:

• fQRS in baseline ECG

• QT dispersion.

• Tp-Te interval and Tp-Te/QTc ratio

• Tp-Te dispersion

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: January 1, 2023
• Est. primary completion date: January 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Subjects with suspected CAD who are referred for elective coronary angiography and/or interventions

Exclusion Criteria:

1. Patients with a history of cardiomyopathy and myocardial infarction (MI), left ventricular hypertrophy (LVH), pathological Q wave on ECG, typical left bundle block or right bundle block, incomplete right bundle block, or paced rhythm on ECG.

2. Patients with severe renal impairment

3. Post CABG patients

4. Patients of acute coronary syndrome

Related Conditions & MeSH terms

• Coronary Aneurysm
• Coronary Artery Ectasia

Intervention

Diagnostic Test:
• Holter, ECG
Incidence of arrhythmias in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.

Locations

Country	Name	City	State
Egypt	Faculty of Medicine Assiut University	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Precence of arrhythmias in 24 hours Holter monitoring	Incidence of arrhythmias in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.	1 year
Secondary	• Heart rate variability in Holter monitoring	Heart rate variability in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.	1 year
Secondary	• Silent ischemia as detected by Holter	Presence pf ischemia in Holter monitoring among coronary artery ectasia patients as compared to normal coronary artery patients.	1 years