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WithDRawal Impact Of Postoperative Beta-Blocker — DROP-BB  

Coronary Artery Bypass Clinical Trial

Official title:
WithDRawal Impact Of Postoperative Beta-Blocker

Clinical Trial Summary

The investigators will evaluate the impact of withdrawing beta-blocker medication after coronary artery bypass surgery with this randomized controlled trial.

Clinical Trial Description

Aim 1: The primary aim is to evaluate the impact of withdrawing BB on exercise capacity (peak oxygen consumption, VO2 max) in patients who underwent CABG. The investigators hypothesize that withdrawing BB 1 month after CABG will improve exercise capacity 2 months after CABG. Aim 2: The secondary objectives are to evaluate the impact of withdrawing BB on a MACCE (major adverse cardiac and cerebrovascular event) and fatigue-related symptoms in patients who underwent CABG. The investigators hypothesize that withdrawing BB after CABG for 1 year will be non-inferior to continuing BB in terms of MACCE incidence. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05414331
Study type Interventional
Source Yale University
Contact Makoto Mori, MD PhD
Phone 475-201-8349
Email makoto.mori@yale.edu
Status Recruiting
Phase N/A
Start date November 4, 2022
Completion date December 2025
View Details
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