Trial to Investigate the in Silico Optimization of Insulin Treatments

Status Recruiting

Clinical Trial Summary

The primary objective of this study is to assess the performance of an in silico designed alternative protocol for control of stress hyperglycemia of inpatients treated for Coronary Artery Bypass Graft (CABG) or valve replacement surgery in the University of Virginia cardiothoracic ICU.

Clinical Trial Description

The hypothesis of the study is that settings for the Glucommander protocol can be optimized in silico to achieve statistically improved low blood glucose index (LBGI) within the subpopulation of CABG and valve replacement patients who both receive Glucommander-based insulin therapy and meet Manufacturer's guidelines for starting with an initial multiplier value of .052, without risking clinically significant increase in exposure to hyperglycemia. ;

Study Design

Related Conditions & MeSH terms

Coronary Artery Bypass

Clinical Trial Details

NCT number	NCT03895138
Study type	Interventional
Source	University of Virginia
Contact	Anna Buhle
Phone	4349898257
Email	ab7ga@virginia.edu
Status	Recruiting
Phase	N/A
Start date	March 19, 2018
Completion date	April 30, 2019

View Details

See also
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