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NCT01118468 Clinical Trial

Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis

Coronary Artery Bypass Clinical Trial

Official title:
Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01118468
Other study ID # 1426
Secondary ID
Status Recruiting
Phase N/A
First received May 5, 2010
Last updated February 6, 2017
Start date January 2010
Est. completion date December 2019

Study information
Verified date February 2017
Source Imperial College London
Contact Justin E Davies, MRCP, PhD
Phone 020 7594 33 86
Email justin.davies@imperial.ac.uk
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Narrowing of the arteries that supply blood to the heart can lead to heart attacks and death. One way of treating this is to use artery and vein grafts from other parts of the body to bypass the narrowing. However, the blood flow from these grafts "competes" with flow through the natural coronary artery. This may contribute to grafts narrowing with time. This protocol aims to determine the pressure changes responsible for this effect. This could improve our understanding of why some grafts last longer than others.

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date December 2019
Est. primary completion date December 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Patients with previous coronary artery bypass grafts undergoing coronary angiography and graft restudy

Exclusion Criteria:

- Patient's with cardiac pacemakers, valvular heart disease, and chronic renal failure

- Unable to consent

- Contraindications to adenosine

- Contraindications to cardiac MRI

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United Kingdom Imperial College NHS Trust London

Sponsors (1)
Lead Sponsor Collaborator
Imperial College London

Country where clinical trial is conducted

United Kingdom, 

See also
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