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Clinical Trial Summary

The purpose of this study is to quantify the amount of corneal staining observed with various marketed contact lens/multipurpose solution combinations. The hypothesis is that there are measurable differences in the amount of corneal staining between the various combinations.


Clinical Trial Description

A series of clinical studies is being conducted at one research site using a double-masked, randomized cross-over design. Each study consists of asymptomatic daily wear soft contact lens wearers observed at baseline and at two and four hours post lens insertion. Corneal staining is being assessed using sodium fluorescein, a cobalt filter and a yellow filter. Subjective comfort assessments are obtained at each visit. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Diagnostic


Related Conditions & MeSH terms


NCT number NCT00381446
Study type Interventional
Source Andrasko, Gary, OD, LLC
Contact Gary J. Andrasko, OD, MS
Phone 614-459-3363
Email gandrask@columbus.rr.com
Status Recruiting
Phase N/A
Start date July 2005
Completion date March 2008

See also
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Completed NCT01335750 - A Clinical Comparison of Marketed Lens Care Solutions With Avaira Lens Brand N/A
Completed NCT01240122 - Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions N/A
Completed NCT00518700 - Comfort Evaluation of a New MPS vs. Replenish in Contact Lens Patients Phase 4
Completed NCT00483795 - Pilot Evaluation of Two Multipurpose Solutions in Regards to Corneal Staining Phase 4