Role of AS-OCT in Assessment of Corneal Perforation

Corneal Perforation Clinical Trial

— OCT  

Official title:

Role of Anterior Segment Optical Coherence Tomography in Assessment of Healing of Thin or Perforated Cornea Treated by Amniotic Membrane Graft and Platelet Rich Plasma Clot

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06422897
• Other study ID #: 1133/04/2024
• Status: Recruiting
• Start date: April 15, 2024
• Est. completion date: June 5, 2024

Study information

• Verified date: May 2024
• Source: Minia University
• Contact: Ahmed A Abdelghany, professor
• Phone: 00201020009630
• Email: ahmeda.abdelghany82[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Assessment of healing of thin and perforated cornea after surgical treatment by anterior segment optical coherence tomography

Description:

• thin and perforated cornea (small perforation) is surgically treated by amniotic membrane graft and platelet rich plasma clot

• anterior segment optical coherence tomography is performed preoperative and 1 month postoperative to assess healing

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 15
• Est. completion date: June 5, 2024
• Est. primary completion date: May 30, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• thin cornea about to perforate

• small corneal perforation

Exclusion Criteria:

• active infection

Related Conditions & MeSH terms

• Corneal Perforation

Intervention

Other:
• anterior segment optical coherence tomography
surgically treated corneal perforation by amniotic membrane graft and platelet rich plasma clot is assessed by anterior segment optical coherence tomography 1 month postoperative

Locations

Country	Name	City	State
Egypt	Faculty of Medicine	Minya

Sponsors (1)

Lead Sponsor	Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Abdelghany AA, Bahrawy ME, Alio JL. Combined Platelet Rich Plasma and Amniotic membrane in the treatment of Perforated Corneal Ulcers. Eur J Ophthalmol. 2022 Jul;32(4):2148-2152. doi: 10.1177/11206721211049100. Epub 2021 Oct 8. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	healing	complete corneal healing	1 month