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Corneal Injuries clinical trials

View clinical trials related to Corneal Injuries.

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NCT ID: NCT04159714 Terminated - Corneal Abrasion Clinical Trials

Bandage Contact Lens Application for the Management of Corneal Abrasion

Start date: September 10, 2019
Phase: N/A
Study type: Interventional

The researchers are trying to understand if the application of a bandage contact lens results in better relief than usual treatment for a corneal abrasion.

NCT ID: NCT03762889 Withdrawn - Corneal Injuries Clinical Trials

Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.

Start date: June 2019
Phase: N/A
Study type: Interventional

This is a randomized controlled trial that seeks to examine the effectiveness of Eyeprotx™ protective goggles in comparison to traditional methods against ocular injury that can occur perioperatively under general anesthesia.

NCT ID: NCT03421548 Withdrawn - Glaucoma Clinical Trials

Implantable Intraocular Pressure Sensor for Glaucoma Monitoring in Patients With Boston Keratoprosthesis Type 1

BKPro
Start date: November 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and performance of the EYEMATE system in patients undergoing concomitant implantation of a BKPro type 1 and an EYEMATE sensor over the 24 months period beginning at implantation.

NCT ID: NCT03295292 Recruiting - Clinical trials for Corneal Scars and Opacities

Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze

Start date: August 1, 2017
Phase: Phase 1
Study type: Interventional

This is a investigator-initiated pilot clinical trial to ascertain the safety and efficacy of application of ex-vivo cultivated limbal stem cells in human eyes for treating Corneal Haze after Photo-Therapeutic/Refractive Keratectomy (PTK/ PRK) and Collagen Cross Linking (CXL). Instead of using adjunctive medical therapy like application of MMC (Mitomycin), a technique of cell delivery with fibrin sealant can be used. These cells are harvested from therapeutically accepted and serologically tested cadaveric corneas. The isolated limbal epithelial and mesenchymal or stromal cell suspension will then be cultured in CGMP laboratories and be tested for sterlity. These cells have also been shown to be effective in treating haze in laser refractive surgery in an animal model. Our initial experience of using these cells in a previous clinical trial showed that they were effective in preventing corneal haze in patients with burns and ulcers.

NCT ID: NCT02948023 Recruiting - Corneal Injuries Clinical Trials

Stem Cells Therapy for Corneal Blindness

ExCell
Start date: August 31, 2016
Phase: Phase 1
Study type: Interventional

This is a investigative initiated, comparative pilot clinical trial to ascertain the safety of application of ex-vivo cultivated limbal stem cells in human eyes for treating different superficial corneal pathologies. Pre-clinical work in murine models have already demonstrated efficacy of this technique in curing murine corneal pathologies.