Clinical Trials Logo
  1. Home
  2. Corneal Endothelial Cell Loss
  3. NCT04072978

Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes

Corneal Endothelial Cell Loss Clinical Trial

Official title:
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes

Clinical Trial Summary

This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).

Clinical Trial Description

On the pre-operative visit, specular microscopy, biometry, applanation tonometry and ocular coherence tomography (OCT) will be performed. The patient will then undergo treatment as per surgeon's discussion/ decision with the patient for implantation of an AC-IOL or SF-IOL. Participation in the study will not impact the management plan in any way. Specular microscopy will be performed wit the CellChek XL (Konan Medical, Irvine, CA). Biometry will be performed with the IOLMASTER (Carl Ziess Meditec, Jena, Germany), and anterior segment and macular OCT will be performed with the Cirrus-HD OCT (Carl Zeiss Metidec, Jena, Germany). EC count, OCT (macula and anterior segment) and specular microscopy will be performed at baseline, week 1, month 1, month 6, 12 and 24. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04072978
Study type Observational
Source Sunnybrook Health Sciences Centre
Contact Cindy Rutz
Phone 416 480 5091
Email cindy.rutz@sunnybrook.ca
Status Recruiting
Phase
Start date September 1, 2019
Completion date January 30, 2025
View Details
See also
  Status Clinical Trial Phase
Completed NCT02470793 - Technique And Results In Endothelial Keratoplasty N/A
Completed NCT02276638 - Comparative Study of Specular Microscopes for Measurements of Cell Density, Coefficient of Variation and Hexagonality
Completed NCT03107000 - Corneal Endothelial Cell Loss After Trabeculectomy Versus Phakotrabeculectomy N/A
Not yet recruiting NCT05522842 - Corneal Endothelium in Diabetics Undergoing Phacoemulsification
Completed NCT02128113 - RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD Phase 2
Completed NCT05447130 - Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome N/A
Recruiting NCT03575130 - Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy Phase 2
Completed NCT06396156 - Anterior Versus Posterior Artisan Intraocular Lens Fixation in Aphakic Children With Insufficient Capsular Support. N/A
Withdrawn NCT03361709 - Effect of Intracameral Dexamethasone After Phacoemulsification in Diabetics on Corneal Endothelial Cell Density Phase 4
Completed NCT02427256 - Second Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
Completed NCT02138266 - Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
Completed NCT04396301 - Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in Phaco Phase 3
Recruiting NCT05847387 - The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study
Recruiting NCT05119270 - Comparison of Phacoemulsification and Corneal Damage Between FLACS and Standard Phaco With Two Handpieces N/A
Recruiting NCT01726790 - Effect of Intravitreal Bevacizumab on Corneal Endothelium N/A