Effect of Intravitreal Bevacizumab on Corneal Endothelium

Status Recruiting

Clinical Trial Summary

To evaluate corneal endothelium cell change after intravitreal Bevacizumab injection

Clinical Trial Description

Intravitreal Bevacizumab has been used by retinal specialist in treatment many retinal diseases. Although it not approved by FDA for treatment. In many In vitro studies, its showed saftey in the eyes especially for corneal endothelium cells, that important cells to keep cornea clear. This study use Confoscan-Corneal confocal microsope to evaluate corneal endothelium before and after intravitreal Bevacizumab injection in routine retinal disease at 6 month follow up. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Corneal Endothelial Cell Loss

Clinical Trial Details

NCT number	NCT01726790
Study type	Observational
Source	Khon Kaen University
Contact	Kasem Yospaiboon, MD
Phone	66823057231
Email	kasem_yod@hotmail.com
Status	Recruiting
Phase	N/A
Start date	August 2011
Completion date	October 2013

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02276638` - Comparative Study of Specular Microscopes for Measurements of Cell Density, Coefficient of Variation and Hexagonality
Completed	`NCT02470793` - Technique And Results In Endothelial Keratoplasty	N/A
Recruiting	`NCT04072978` - Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
Completed	`NCT03107000` - Corneal Endothelial Cell Loss After Trabeculectomy Versus Phakotrabeculectomy	N/A
Not yet recruiting	`NCT05522842` - Corneal Endothelium in Diabetics Undergoing Phacoemulsification
Completed	`NCT02128113` - RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD	Phase 2
Completed	`NCT05447130` - Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome	N/A
Recruiting	`NCT03575130` - Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy	Phase 2
Completed	`NCT06396156` - Anterior Versus Posterior Artisan Intraocular Lens Fixation in Aphakic Children With Insufficient Capsular Support.	N/A
Withdrawn	`NCT03361709` - Effect of Intracameral Dexamethasone After Phacoemulsification in Diabetics on Corneal Endothelial Cell Density	Phase 4
Completed	`NCT02427256` - Second Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
Completed	`NCT02138266` - Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
Completed	`NCT04396301` - Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in Phaco	Phase 3
Recruiting	`NCT05847387` - The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study
Recruiting	`NCT05119270` - Comparison of Phacoemulsification and Corneal Damage Between FLACS and Standard Phaco With Two Handpieces	N/A