Fuchs' Endothelial Dystrophy Clinical Trial
Official title:
DSAEK- Postoperative Positioning and Transplant Dislocation
Corneal transplant is a surgical procedure where a damaged or diseased cornea is replaced by
donated corneal tissue (the graft) in its entirety (penetrating keratoplasty) or in part
(lamellar keratoplasty). One type of lamellar keratoplasty is DSAEK (Descemet's Stripping
Automated Endothelial Keratoplasty), where only the damaged posterior section of the cornea
is replaced.
The purpose of this study is to investigate how immediate postoperative positioning of the
patient affects the dislocation rate of the corneal graft. Since this is a new surgical
method, little scientific documentation has been published in this area.
Corneal transplant is a surgical procedure where a damaged or diseased cornea is replaced by
donated corneal tissue (the graft) in its entirety (penetrating keratoplasty) or in part
(lamellar keratoplasty). One type of lamellar keratoplasty is DSAEK (Descemet's Stripping
Automated Endothelial Keratoplasty), where only the damaged posterior section of the cornea
is replaced.
To get the graft in the right position inside the eyes anterior chamber, the anterior
chamber is fully filled with air, and the patient is placed in a supine position looking
facing up for different amount of time depending on the surgeon. In this way the air bubble
will press the graft in the right position and prevent dislocation. Our experience is that
since the anterior chamber of the eye already is fully filled with air, it does not matter
how the patient is positioned postoperatively regarding graft dislocation.
Our hypothesis is that the immediate postoperative positioning is insignificant. If this can
be significantly proved this may enhance the patients comfort postoperatively.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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