Clinical Trials Logo

Clinical Trial Summary

60% of the patients hospitalized in intensive care and sedated suffer from insufficient inferior eyelid occlusion. Thus, they are at risk for corneal damage (estimated risk 20% to 57%). The prevention of such corneal damage can be done using several techniques (artificial tears, eyelid occlusion dressing, aqueous gel). The efficacy of these techniques has never been compared in a rigorous study. Therefore it is not yet possible to determine an evidence-based strategy to prevent corneal damage in intensive care patients.

This study aims at assessing the efficacy of primary prevention of corneal lesions in intensive care patients, in order to elaborate an evidence-based nursing protocol.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02348242
Study type Interventional
Source Fondation Ophtalmologique Adolphe de Rothschild
Contact
Status Completed
Phase N/A
Start date December 2014
Completion date February 2016

See also
  Status Clinical Trial Phase
Completed NCT02291731 - Autologous Serum Eye Drops With Contact Lenses for Corneal Epithelial Defects N/A
Completed NCT00810472 - Functional Antigen Matching in Corneal Transplantation N/A
Completed NCT00029185 - Study of Dehydrex in Patients With Corneal Erosion N/A
Enrolling by invitation NCT03436576 - Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye Phase 3
Completed NCT02344732 - Effect of Systemic Oxygen on Corneal Epithelial Wound Healing in Diabetic Patients Undergoing Pars Plana Vitrectomy N/A
Recruiting NCT06451172 - Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis Early Phase 1
Not yet recruiting NCT05833737 - Corneal Findings in Patients Treated With Belantamab Mafodotin
Completed NCT04421300 - A Randomized Study of Smile Exercise for Dry Eye N/A
Completed NCT00396188 - Screening Aid to Identify Corneas That May Have Pathologies or Other Conditions Phase 1
Terminated NCT03029104 - Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas Phase 2
Completed NCT00050466 - Dynamic Light Scattering and Keratoscopy for Corneal Examination N/A
Recruiting NCT04164407 - Keratoconus, Corneal Diseases and Transplant Registry
Withdrawn NCT05052554 - Study With QR-504a to Evaluate Safety, Tolerability & Corneal Endothelium Molecular Biomarker(s) in Subjects With FECD3 Phase 1
Terminated NCT00447187 - Study to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failure in Subjects at Increased Immunological Risk Phase 3
Completed NCT00491439 - Using in Vivo Confocal Microscope to Evaluate the Corneal Wound Healing After Various Ocular Surgeries N/A