Corneal Diseases Clinical Trial
Official title:
Corneal Analysis - Pathology Detection Aid
The purpose of this study is to determine the ability of a proprietary software screening tool to discriminate normal corneas (front surface of the eye) from previously diagnosed corneal conditions (diseases/surgeries/pathologies) and to determine the repeatabiltity and reproducibility of the Atlas II corneal topographer in normal human corneas.
1. To establish reference values for SF, CIM, and TKM in subjects with normal corneas.
2. To establish reference values for SF, CIM, and TKM in subjects who underwent myopic
laser vision correction.
3. To establish reference values for SF, CIM, and TKM in subjects who underwent hyperopic
laser vision correction.
4. To establish reference values for SF, CIM, and TKM in subjects who were diagnosed to
have keratoconus.
5. To establish reference values for SF, CIM, and TKM in subjects with history of
orthokeratology.
6. To establish reference values for SF, CIM, and TKM in subjects with previously
diagnosed corneal conditions (diseases/pathologies/surgeries) affecting the corneal
surface that are not listed above.
7. To determine the repeatabiltity and reproducibility of the Atlas II corneal topographer
in normal human corneas using true elevation data and axial curvature.
8. To determine the sensitivity, specificity, and accuracy of the Pathfinder II Corneal
Analysis software in discriminating normal corneas from previously diagnosed corneal
conditions (diseases/pathologies/surgeries) affecting the corneal surface (Phase II).
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Observational Model: Case Control, Time Perspective: Cross-Sectional
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