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Corneal Blindness clinical trials

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NCT ID: NCT01950598 Completed - Corneal Blindness Clinical Trials

Frozen Versus Fresh Corneal Carriers for the Boston KPro Type I Donor Carriers

Start date: September 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether frozen corneas are as safe and effective as fresh corneas for use as carriers with the Boston Keratoprosthesis type I (KPro) over long term follow-up. Corneal transplantation is typically performed using fresh, transparent corneas. With KPro surgery, the corneal transplant only serves as a carrier to suture the KPro in place. The cornea used in KPro surgery does not need to be clear like a normal transplant. Frozen corneal tissue can be used to repair the cornea in cases of emergency but the tissue is not transparent and does not allow good vision. We hypothesize that frozen grafts are equivalent as fresh grafts when used as carrier for the KPro.