Correlation Analysis Between Corneal Biomechanics and Anterior Segment

Corneal Biomechanics Clinical Trial

Official title:

Correlation Analysis Between In-vivo Corneal Biomechanical Properties and Anterior Segment in Chinese Population

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06109636
• Other study ID #: KY2023025
• Status: Completed
• Start date: March 4, 2023
• Est. completion date: October 1, 2023

Study information

• Verified date: October 2023
• Source: Tianjin Eye Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Evaluation of the ciliary muscle thickness, area, and anterior chamber angle, as well as anterior sclera thickness in subjects, to investigate the relationship between these measurements and corneal biomechanics. Clarify whether aqueous humor displacement, anterior sclera, and ciliary muscles influence the assessment of in vivo corneal biomechanics.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: October 1, 2023
• Est. primary completion date: October 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

1. Best corrected visual acuity (BCVA) = 20/20;

2. No other eye diseases except myopia and astigmatism;

3. The cornea was transparent, and there was no cloud or pannus;

Exclusion Criteria:

1. Corneal disease;

2. Ocular trauma;

3. Previous ocular surgery;

4. Any anterior segment diseases except cataract;

5. Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination;

6. Pregnant and lactating women;

Related Conditions & MeSH terms

• Corneal Biomechanics

Intervention

Other:
• Pentacam, Corvis ST and Casia2
scleral and ciliary muscle thickness were obtained by Casia2, biomechanical parameters were obtained by Pentacam and Corvis ST

Locations

Country	Name	City	State
China	Tiajin Eye Hospital	Tianjin	Tianjin

Sponsors (1)

Lead Sponsor	Collaborator
Tianjin Eye Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	scleral and ciliary muscle thickness	The thickness of scleral and ciliary muscle(Casia2, quantitative data through the utilization of its integrated ruler system)	one year
Primary	biomechanical parameters	The biomechanical parameters(Corvis ST, exporting the quality-assured csv files to analysis)	one year